New Clinical Tool to Measure & Monitor Blood Flow

Ultrasound is a ubiquitous clinical tool because it is a safe and reliable means to check the functioning of soft tissue structures inside the body.

DUPLEX imaging diagnostic systems requires relatively expensive equipment and incurs the expense of a skilled operator for repeatable measurements.

DUPLEX uses a transducer contains a large number of independently controllable ultrasound transmitter/receiver elements.
A beam is formed and scanned by control electronics.
Imaging software performs analysis of reflected echo to form an image.
A skilled operator is required to manipulate the complex controls to image the desired internal structures.

Doppler ultrasound is a quick subjective confirmation of blood flow. It is a handheld pen-shaped device usually with an audible sound characterizing the velocity of blood.

Used as a bedside confirmation of circulation – sounds normal, “whoosh – whoosh”.
Highly dependent on orientation, required to “angle the device for maximum signal”.
Used for locating and checking circulation, not a quantitative measurement.

Arterium Medical’s patented Doppler sensor redefined for reliable quantitative monitoring.

• Orientation variability of alignment with artery now significantly reduced.

- US Patent 6,346,081 (Vilkomerson) invented a simple way to generate a focused beam without the complexity of DUPLEX. 6,346,081
- US Patent 6,726,628 (Vilkomerson) furthered invention as a screening device that provided consistent measurements by untrained operators. 6,726,628
- US Patent 7,963,920 (Vilkomerson) invented the simple focused beam on a thin film flexible material. 7,963,920
- US Patent 8,852,110 (Vilkomerson) furthered invention to multiple beams on a thin film. 8,852,110

• Efficiency of thin film sensor significantly improved. Now a viable disposable thin film ultrasound device can be taped in place over a patient’s artery for continuous monitoring.

Conventional ultrasound use a piezoelectric ceramic material (PZT). This ceramic must be minutely sliced to form the individually controllable elements of an ultrasound beam. The ceramic PZT used in DUPLEX imaging systems has high manufacturing cost but the energy conversion efficient is good.

A plastic-like polymer, polyvinylidene difluoride (PVDF) is also known to have piezoelectric property. This crystalline material in a solvent can be easily applied as a thin film. However the efficiency of energy conversion is less than PZT ceramics.

- US Patent 8,564,177 (Vilkomerson) invented a layered piezo-polymer structure that significantly increases the ultrasound energy coupling through the skin (transdermal). 8,564,177

• Electronics can be reduced to a single chip to determine real time arterial blood flow velocity using available silicon level library functions.

Digital Audio chips operate within a similar frequency range and accuracy.
Integrated Bluetooth communications capabilities are readily available as silicon modules.
Battery powered low cost consumer devices available for wireless digital audio.

• Skin attachment materials and ultrasound gel pads are readily available from 3rd party vendors.